Mikrotiterplattenanalyse von Cytochrom P450 Metaboliten

Vorhersage struktureller und biochemischer Eigenschaften von Cytochrom P450-Monooxygenasen und Laccasen

In the following update procedure a new version with a refined classification was realized and, besides integrating new sequences and structures, the CYPED was extended by biochemical properties, and by adding new functionalities. The amount of sequences and structures almost doubled. The CYPED entries could be linked to the entries of the CPK (Cytochrome P450 Knowledgebase, (Lisitsa et al., 20...

Porphyrins in Synthetic Membranes as Mimics for Cytochrom e P450

The role of general metabolites in the biosynthesis of natural products. IV. Incorporation of U-14C ribose and U-14C fructose in marrubiin terpene.

Min.mg konstant. Für die Aktivität des aus den Wurzeln erhaltenen Digipurpurogenins berechnet sich ein Wert von etwa 4200 Imp./Min. gleich 3,5-10"2% der eingesetzten Aktivität. Für das gesamte Digipurpurogenin ergibt sich damit eine Einbaurate von etwa 0,1 Prozent. Als weitere Metaboliten wurden in den Blättern nach Hydrolyse Digitoxigenin und Gitoxigenin nachgewiesen, während diese Substanzen ...

Effect of homomeric P450-P450 complexes on P450 function.

Previous studies have shown that the presence of one P450 enzyme can affect the function of another. The goal of the present study was to determine if P450 enzymes are capable of forming homomeric complexes that affect P450 function. To address this problem, the catalytic activities of several P450s were examined in reconstituted systems containing NADPH-POR (cytochrome P450 reductase) and a si...

JALDA's Interview with Professor Luise von Flotow

Luise von Flotow is a Professor of Translation Studies at the School of Translation and Interpretation, University of Ottawa, Canada. She got her BA in German and French from the University of London (1974) and her MA in French from the University of Windsor (1985) and her Ph.D. in French from the University of Michigan (1991). Professor von Flotow was the director of the School of Translation ...